P. Gourdon et al., SEQUENCE-ANALYSIS OF THE ADE2 GENE CODING FOR PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE IN SCHWANNIOMYCES-OCCIDENTALIS, Yeast, 11(13), 1995, pp. 1289-1293
We have determined the nucleotide sequence of a 3.3 kb fragment contai
ning the gene (ADE2) encoding phosphoribosylaminoimidazole carboxylase
(AIRC) from the yeast Schwanniomyces occidentalis. Translation of a 1
671 bp open reading frame predicts a protein of 557 amino acids which
has significant homology to AIRC from Saccharomyces cerevisiae and Sch
izosaccharomyces pombe. The 5' untranslated region of the S occidental
is gene contains a sequence corresponding to the consensus binding sit
e of the S. cerevisiae transcription regulatory proteins GCN4, BAS1 an
d BAS2. The ADE2 gene nucleotide sequence has received the GenBank Acc
ession Number U23210.