There is a limited experience with catheter ablation for treatment of
ventricular tachycardia (VT) in Chagasic cardiomyopathy. A 30-year-old
woman experienced episodes of palpitations and syncope due to attacks
of VT. A diagnosis of Chagas disease was established on a biological
basis. Two-dimensional echo and contrast ventriculography showed an ap
ical aneurysm with thrombus. Surgery was indicated to resect the aneur
ysm and ablate the VT. Ventricular tachycardia recurred 1 month later
despite therapy, including amiodarone. Two clinical frequent and well-
tolerated tachycardias were identified. The site of origin was located
in the right ventricular apex and in the apical-lateral wall of the l
eft ventricle, respectively. Catheter ablation was performed at two si
tes with DC shocks (total energy 600 J) after unsuccessful radiofreque
ncy ablation. Holter recordings performed during the postoperative per
iod showed only infrequent extrasystoles. After follow-up of 24 months
the patient remains asymptomatic. Drug-refractory VT in Chagasic card
iomyopathy can be ablated by medium-energy DC shocks after failure of
radiofrequency ablation.