PRIMARY BASALOID-SQUAMOUS CELL-CARCINOMA OF THE TRACHEA

Basaloid squamous cell carcinoma (BSCC) is an unusual but well-establi shed entity, primarily in the upper aerodigestive tract, composed of b asaloid cells associated with dysplastic to neoplastic squamous cells, and characterized by an aggressive and rapidly fatal course. To date, BSCC originating in the trachea has not been reported, In this articl e, the authors describe the clinical, gross, and microscopic pathologi c, histochemical, and immunohistochemical features of two cases of BSC C arising in the trachea. Features distinguishing this entity from oth er, more common tumors of the trachea, including metastases and direct extension from other sites of origin, are also discussed.