PHOSPHONOTHRIXIN, A NOVEL HERBICIDAL ANTIBIOTIC PRODUCED BY SACCHAROTHRIX SP ST-888 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES

Authors
TAKAHASHI E KIMURA T NAKAMURA K ARAHIRA M IIDA M
Citation
E. Takahashi et al., PHOSPHONOTHRIXIN, A NOVEL HERBICIDAL ANTIBIOTIC PRODUCED BY SACCHAROTHRIX SP ST-888 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 48(10), 1995, pp. 1124-1129
Citations number
13
Categorie Soggetti
Pharmacology & Pharmacy",Immunology,"Biothechnology & Applied Migrobiology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
48
Issue
10
Year of publication
1995
Pages
1124 - 1129
Database
ISI
SICI code
0021-8820(1995)48:10<1124:PANHAP>2.0.ZU;2-F
Abstract
A novel herbicidal compound, phosphonothrixin, was found in the fermen tation broth of Saccharothrix sp. ST-888 cultured on a vegetable juice medium. The compound exhibiting acidic and hydrophilic properties was obtained when the fermentation broth of ST-888 was subjected to ion e xchange chromatography, gel filtration chromatography and ion-pair chr omatography. Phosphonothrixin significantly inhibited germination of g ramineous and broadleaf weeds. Foliar application of this antibiotic g ave rise to chlorosis in all of the plants tested.