E. Takahashi et al., PHOSPHONOTHRIXIN, A NOVEL HERBICIDAL ANTIBIOTIC PRODUCED BY SACCHAROTHRIX SP ST-888 .1. TAXONOMY, FERMENTATION, ISOLATION AND BIOLOGICAL PROPERTIES, Journal of antibiotics, 48(10), 1995, pp. 1124-1129
A novel herbicidal compound, phosphonothrixin, was found in the fermen
tation broth of Saccharothrix sp. ST-888 cultured on a vegetable juice
medium. The compound exhibiting acidic and hydrophilic properties was
obtained when the fermentation broth of ST-888 was subjected to ion e
xchange chromatography, gel filtration chromatography and ion-pair chr
omatography. Phosphonothrixin significantly inhibited germination of g
ramineous and broadleaf weeds. Foliar application of this antibiotic g
ave rise to chlorosis in all of the plants tested.