PURPOSE: To assess the comparative and adjunctive diagnostic value of
double-contrast barium enema examination (DCBE) and colonoscopy in cas
es of idiopathic inflammatory bowel disease. MATERIALS AND METHODS: Ra
diographic and endoscopic findings were correlated, with use of a stan
dardized evaluation sheet, in a prospective, blinded study in 99 patie
nts with previously well-established Crohn disease of the colon (CD [n
= 51]) or ulcerative colitis (UC [n = 481]). RESULTS: Overall, substa
ntial to almost perfect agreement was found in more than 80% of scores
with respect to the items of the standardized evaluation sheet in the
colon segments depicted with both imaging modalities. Almost perfect
agreement (K > 60%) was found for two essential diagnostic and differe
ntial diagnostic features: aphthoid erosions and fine granularity. CON
CLUSION: DCBE and colonoscopy are complementary imaging modalities for
optimal detection of all mucosal and structural colon lesions, except
inflammatory lesions without distortion of the mucosal relief and sma
ll numbers of inflamed superficial erosions and ulcers.