HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF UROCANIC ACID ISOMERS IN COSMETIC PRODUCTS

Authors
DEORSI D GAGLIARDI L CHIMENTI F TONELLI D
Citation
D. Deorsi et al., HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF UROCANIC ACID ISOMERS IN COSMETIC PRODUCTS, Chromatographia, 41(5-6), 1995, pp. 370-372
Citations number
10
Categorie Soggetti
Chemistry Analytical","Biochemical Research Methods
Journal title
Chromatographia → ACNP
ISSN journal
00095893
Volume
41
Issue
5-6
Year of publication
1995
Pages
370 - 372
Database
ISI
SICI code
0009-5893(1995)41:5-6<370:HLDOUA>2.0.ZU;2-X
Abstract
A method has been developed for the determination of trans and cis uro canic acid in oil-in-water cosmetic emulsions. It involves an extracti on of the sample in 1 : 3 methanol-aqueous NaOH (10(-3) M), by ultraso nication, which leads to quantitative recoveries, and a reversed-phase HPLC isocratic elution for the analysis of the extract. Chromatograph y is performed on a C18 column using 0.1 M sodium perchlorate (pH 3.0) -acetonitrile 98 : 2 (v/v), as the mobile phase, and UV detection at 2 63 nm. The separation of the isomers is good. Linearity and precision of the method have been assessed.