We present 10 cases of meningiomas occurring after high-dose irradiati
on for other brain tumours. These constitute 3.7% of 272 patients with
meningiomas treated in our unit over 10 years. The clinical and patho
logical features of the 10 cases were added to those of 69 previous ca
ses documented in the literature and compared with the features of our
262 spontaneous meningiomas. The literature on 119 cases of low-dose
radiation-induced meningiomas was also reviewed. Malignant histologica
l features and multiplicity were more common in the radiation-induced
meningiomas (p < 0.01). Increasing long-term survival rates following
radiotherapy for primary intracranial rumours, particularly in childho
od, may lead to an increased incidence of postirradiation meningiomas.