ONE-POT PROCEDURE FOR THE SYNTHESIS OF N-FUMAROYL-2-OXAZOLIDINONES

Authors
KNOL J FERINGA BL
Citation
J. Knol et Bl. Feringa, ONE-POT PROCEDURE FOR THE SYNTHESIS OF N-FUMAROYL-2-OXAZOLIDINONES, Synlett, (10), 1995, pp. 1025
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
10
Year of publication
1995
Database
ISI
SICI code
0936-5214(1995):10<1025:OPFTSO>2.0.ZU;2-U
Abstract
Reaction of maleic anhydride with 2-oxazolidinone in the presence of t riethylamine yields mono functionalized maleic acid, which is transfor med into functionalized N-fumaroyl-2-oxazolidinones in 45-56% overall yields by treatment with oxalyl chloride and subsequent reaction with nucleophiles.