Wx. Lu et L. Xia, 3-DIMENSIONAL SIMULATION OF EPICARDIAL POTENTIALS USING A MICROCOMPUTER-BASED HEART-TORSO MODEL, Medical engineering & physics, 17(8), 1995, pp. 625-632
Previous cardiac simulation studies have focused on simulating the act
ivation isochrones and subsequently the body surface potentials. Epica
rdial potentials, which are important for clinical applications as wel
l as for electrocardiography inverse problem studies, however, have us
ually been neglected. This paper presents a procedure of simulating ep
icardial potentials using a microcomputer-based heart-torso model with
real geometry The heart model developed earlier which was composed of
more than 60,000 cell units was used in this study. To simulate the e
picardial potentials, an epicardial surface model which enclosed the w
hole heart was constructed. The heart model, together with the epicard
ial surface model, are mounted in an inhomogeneous human torso model.
Electric dipoles, which are proportional to the spatial gradient of th
e action potential, are generated in all cell units. These dipoles giv
e rise to a potential distribution on the epicardial surface, which is
calculated by means of the boundary element method. The simulated epi
cardial potential maps during a normal heart beat and in patients with
left bundle branch block (LBBB) are in close agreement with those rep
orted in the literature.