A mouse cDNA encoding a human homologue of heme oxygenase-2 (HO-2) was
isolated. The deduced protein contains 315 amino acids and has a calc
ulated molecular mass of 35.8 kDa. The nucleotide sequence is 85.6% id
entical and the amino acid sequence 87% identical to those of the huma
n protein. The corresponding mRNA is present in brain and testis, but
not in ovary, kidney, liver, or spleen.