INVASIVE CRYPTOCOCCOSIS DURING AN IDIOPAT HIC CD4 LYMPHOCYTOPENIA WITH MYOSITIS AND CUTANEOUS MANIFESTATIONS

We report a case of invasive cryptococcosis in a patient with idiopath ic CD4 T lymphocytopenia. The presenting feature as a profound muscle weakness is particular. The diagnostic is evocated by the presence of encapsulated yeast on the histology of the skin and of the muscle and also in cerebrospinal fluid, blood-culture and bronchoalveolar lavage. The disease control is obtained with amphotericin B during two months a half and itraconazole all life long because of the persistance of p rofound CD4 T lymphocytopenia unexplained.