Aj. Lincoln et al., SENSORY MODULATION OF AUDITORY-STIMULI IN CHILDREN WITH AUTISM AND RECEPTIVE DEVELOPMENTAL LANGUAGE DISORDER - EVENT-RELATED BRAIN POTENTIAL EVIDENCE, Journal of autism and developmental disorders, 25(5), 1995, pp. 521-539
Three groups of age- and PIQ-matched children (Autism, Receptive Devel
opmental Language Disorder, and normal controls) participated in two e
vent-related brain potential (ERP) experiments. Each of these experime
nts was aimed at evaluating whether either of the two clinical groups
of children demonstrated abnormalities in two auditory ERP components
N1 and P2, which are known to be dependent on stimulus characteristics
(frequency, intensity, and probability), and believed to be generated
within primary and secondary cortex. Results of Experiment 1 provide
partial support for the idea that both clinical groups failed to fully
process changes in stimulus intensity as indexed by the N1 component.
Results are discussed in reference to potential abnormalities in sero
tonergic regulation of auditory cortex.