IR AND TURBIDITY STUDIES OF VITAMIN-E-CHOLESTEROL-PHOSPHOLIPID MEMBRANE INTERACTIONS

Binary and tertiary mixture of alpha-tocophenol, cholesterol and dimyr istoylphospharidylcholine in the form of multilamellar liposomes were investigated by Fourier Transform infrared and visible spectroscopy. R esults of the FTIR and turbidity experiments indicate that alpha T dec reases or diminishes the effect of cholesterol on the frequency and th e bandwidth of the C-H stretching, CH2 scissoring and C=O stretching b ands in FTIR spectra and the turbidity measurements (recorded as absor bance values at 440 nm) in phospholipid model membranes.