Collaborative research programs have a significant impact on,he struct
ure of national innovation systems by creating and strengthening netwo
rks which are essential for breeding. innovation clusters. These netwo
rks involve both technology and market stakeholders and are extended t
o include industry, research and technology producers. Network activit
ies have resulted in setting priority in research and linking research
fields that have high potential to coalesce into distinct technologic
al clusters. This paper examines the processes by which innovation clu
sters are formed in research collaborations by analysing the work prog
rams of 51 Australian Cooperative Research Centres (CRCs). The paper a
lso provides an analytical framework to determine the direction of nat
ional research setting through cluster analysis. The author employs a
methodology called 'co-occurrence of words' in cluster construction. I
t is argued that the iterative process of innovation cluster formation
is an effective form of organizing a national system of innovation. T
hese clusters enable public policy makers to identify complementaritie
s between generation, acquisition and diffusion of knowledge across a
range of innovations rather than a single innovation.