INTRAMOLECULAR ALLYLSILANE-ALDEHYDE CYCLI ZATION IN THE SYNTHESIS OF MEDIUM RING COMPOUNDS

Authors
THOMAS AE JENKINS PR ROBINSON G SIMONS C ALGUACIL R TAPIA YRA
Citation
Ae. Thomas et al., INTRAMOLECULAR ALLYLSILANE-ALDEHYDE CYCLI ZATION IN THE SYNTHESIS OF MEDIUM RING COMPOUNDS, Anales de quimica, 91(3-4), 1995, pp. 206-213
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Anales de quimica → ACNP
ISSN journal
11302283
Volume
91
Issue
3-4
Year of publication
1995
Pages
206 - 213
Database
ISI
SICI code
1130-2283(1995)91:3-4<206:IACZIT>2.0.ZU;2-V
Abstract
The allylsilane-aldehyde 12a-c, containing a chiral centre. have been prepared to study their intramolecular cyclization. These compounds cy clized to 6, 7 and 8 membered rings containing a second chiral centre. The results indicate that in these cases the chiral centre of the sub strates 12a-c have very little influence upon the diastereoselectivity of the cyclization.