Y. Ueta et al., WATER-DEPRIVATION IN THE RAT INDUCES NITRIC-OXIDE SYNTHASE (NOS) GENE-EXPRESSION IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI, Neuroscience research, 23(3), 1995, pp. 317-319
We examined the effects of water deprivation on nitric oxide synthase
(NOS) gene expression in the rat hypothalamic paraventricular (PVN) an
d supraoptic nuclei (SON), using in situ hybridization histochemistry.
Dehydration caused a significant increase in NOS gene transcripts in
the PVN and SON but not in the subfornical organ (SFO). The results su
ggest that dehydration has a major effect on the NOS gene expression i
n the PVN and SON.