Chemical and mineral composition of the Moon's middle mantle (270-500
km) has been determined by means of mathematic simulation of phase rel
ations and physical properties in the system CaO-FeO-MgO-Al2O3-SiO2. C
onstraints have been set on the contents of petro-genic oxides. Physic
al properties of pyroxenite models with 50-52% SiO2 and 15-16% FeO hav
e been shown to well correlate with the experimental seismic data and
geophysical constraints on the density and momentum. Middle mantle has
bimineral pyroxenite composition (pyroxene + olivine) and enriched in
silica and iron as compared to the lower mantle. No one of the consid
ered geochemical models of total composition of the Moon obey the seis
mic constraints both in the upper, middle, and lower mantle simultaneo
usly. Phase transition spinel peridotite --> garnet peridotite can not
explain the nature of seismic boundaries at the depth of 270 and 500
km. A conclusion has been made about chemical stratification of lunar
mantle.