The authors describe the case of a young African girl born with a radi
al club hand associated with a pedicled floating thumb, no other ortho
paedic malformation was detected. A ventricular septal defect necessit
ated surgery in emergency. In front of such malformative association,
the Holt-Oram syndrome has been evoked. The aim of this study has been
to review the etiology and classification of this rather rare malform
ative association, as well as to describe the therapeutic attitudes an
d surgical techniques proposed by various authors towards the radial c
lub hand (1, 3, 5, 6, 7, 12).