EFFECTS OF ACUTE PRENATAL ETHANOL EXPOSURE ON BERGMANN GLIA CELLS EARLY POSTNATAL-DEVELOPMENT

Authors
PEREZTORRERO E DURBAN P GRANADOS L GUTIERREZOSPINA G CINTRA L DIAZCINTRA S
Citation
E. Pereztorrero et al., EFFECTS OF ACUTE PRENATAL ETHANOL EXPOSURE ON BERGMANN GLIA CELLS EARLY POSTNATAL-DEVELOPMENT, Brain research, 746(1-2), 1997, pp. 305-308
Citations number
24
Categorie Soggetti
Neurosciences
Journal title
Brain research → ACNP
ISSN journal
00068993
Volume
746
Issue
1-2
Year of publication
1997
Pages
305 - 308
Database
ISI
SICI code
0006-8993(1997)746:1-2<305:EOAPEE>2.0.ZU;2-Z
Abstract
Effects of acute ethanol exposure during the prenatal phase of Bergman n glia cell (Bgc) generation were evaluated in three postnatal days. E thanol exposed rats showed Bgc with reduced soma size, decreased numbe r and width of their fibers, and increased fiber length, when compared with control animals. These differences, however, were significant at postnatal day 12. Our results demonstrate that acute, prenatal exposu re to ethanol during critical stages of brain development disrupts Bgc early postnatal development.