Splenic abscesses are rare and account for only 2 to 5.4% of all intra
-abdominal suppurations. Hematogenous dissemination during septicemia
or endocarditis, infection of an infarct or post-traumatic hematoma, a
nd spread of a neighboring infection are the mechanisms that can lead
to development of a splenic abscess. Hemoglobinopathies, diabetes mell
itus, and immune depression are the main risk factors. Clinical sympto
ms are often inconspicuous and nonspecific, and until recently the dia
gnosis was often established only upon autopsy. Painful enlargement of
the spleen in a febrile patient should suggest a splenic abscess. The
most common causative agents are Staphylococcus aureus, streptococci,
and Gramnegative rods. Ultrasonography and computed tomography readil
y demonstrate the abscess. and can be used to guide percutaneous aspir
ation and/or drainage and to monitor the course. Percutaneous aspirati
on or drainage with appropriate antimicrobial therapy usually ensures
recovery. Splenectomy is indicated if percutaneous drainage fails.