K. Dossche et al., FREE-HAND SEWN ALLOGRAFTS, STENTLESS (PRIMA-EDWARDS) AND STENTED (CESA) PORCINE BIOPROSTHESES - A COMPARATIVE HEMODYNAMIC-STUDY, European journal of cardio-thoracic surgery, 9(10), 1995, pp. 562-566
In a retrospective, non-randomized study, the clinical and hemodynamic
properties of 50 consecutively implanted hand-sewn allografts (group
I), 50 stentless bioprostheses (group II) and 50 stented bioprostheses
(group III) were compared. Preoperative hemodynamic and clinical data
were identical in the three groups, except for age (group I: 54.4 +/-
8.7, group II: 67.0 +/- 5,1, group III: 70.0+/-5.1). Peak and mean gr
adients and flow characteristics with echo Doppler were performed at 1
week, 6 and 12 months, For the 21, 23 and 25 diameter prostheses, gro
up differences between groups II and III in peak and mean gradients we
re not significant after 1 week and 1 year. In all groups, allografts
had significantly lower gradients. Regurgitation (I-II) was present af
ter 1 week and 1 year in group I: in 17/48 and 22/42 patients respecti
vely, in group 117/49 and 11/44 patients and in group III: in 1/49 and
2/44 patients. Early mortality and morbidity were comparable in all g
roups. Allografts have superior hemodynamic properties. Differences in
gradients in groups II and III were not significant, though differenc
es in technique allowed the implantation of a larger bioprostheses in
group II. Regurgitation was most prominent in the allograft group. Imm
ediate postoperative results were not influenced by the type of prosth
esis.