RESOLUTION OF HEPATITIS-B VIRUS-RELATED MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS AFTER ORTHOTOPIC LIVER-TRANSPLANTATION

The most well-described renal disease associated with hepatitis B viru s (HBV) infection is membranous glomerulonephritis; membranoproliferat ive glomerulonephritis is described much less frequently. The course o f HBV-associated renal disease after liver transplantation has not bee n described to date. We present a 15-year-old girl with HBV-associated membranoproliferative glomerulonephritis and end-stage liver disease, in whom, after cadaver liver transplantation, clinical and histologic al resolution of renal disease was observed. Resolution was associated with diminution of circulating HBV surface antigen levels.