Cryosurgery using liquid nitrogen is a method for treating benign- and
low-malignant skeletal tumors. The advantage of preserving the suppor
tive function of bone should be compared to the risk for its complicat
ions; postoperative fracture is well known, but less so the occurrence
of intraoperative venous gas embolism. This paper describes 17 patien
ts: 2 patients who had serious hemodynamic complications during cryosu
rgery and a study of 15 patients in whom end-tidal N-2 tension was mea
sured in an attempt to investigate the clinical incidence of venous ga
s embolism during cryosurgery. In the 15 cases analyzed, we did not de
tect any exhaled N-2 during cryosurgery. (C) 1995 Wiley-Liss, Inc.