ENZYMATIC-SYNTHESIS OF YIGSR - LAMININ PENTAPEPTIDE FRAGMENT-DERIVATIVES

Citation
Ey. Terenteva et al., ENZYMATIC-SYNTHESIS OF YIGSR - LAMININ PENTAPEPTIDE FRAGMENT-DERIVATIVES, Bioorganic & medicinal chemistry letters, 5(21), 1995, pp. 2523-2526
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
ISSN journal
0960894X
Volume
5
Issue
21
Year of publication
1995
Pages
2523 - 2526
Database
ISI
SICI code
0960-894X(1995)5:21<2523:EOY-LP>2.0.ZU;2-K
Abstract
An enzymatic synthesis of Ac-Tyr-Ile-Gly-Ser-Arg-OH, its amide and p-n itroanilide starting with Boc-Ile-Gly-Ser-OCH3 is described, The react ions were performed in organic solvents using subtilisin and alpha-chy motrypsin sorbed on macroporous silica surface as the catalysts.