An enzymatic synthesis of Ac-Tyr-Ile-Gly-Ser-Arg-OH, its amide and p-n
itroanilide starting with Boc-Ile-Gly-Ser-OCH3 is described, The react
ions were performed in organic solvents using subtilisin and alpha-chy
motrypsin sorbed on macroporous silica surface as the catalysts.