A PREDICATIVE MODEL FOR CERTAIN DIRECTED METALATIONS .3. THE ABILITY OF A METHYL SUBSTITUENT TO INFLUENCE THE DIRECTED METALATION OF ANISOLE

Authors
SLOCUM DW THOMPSON J FRIESEN C
Citation
Dw. Slocum et al., A PREDICATIVE MODEL FOR CERTAIN DIRECTED METALATIONS .3. THE ABILITY OF A METHYL SUBSTITUENT TO INFLUENCE THE DIRECTED METALATION OF ANISOLE, Tetrahedron letters, 36(45), 1995, pp. 8171-8174
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
36
Issue
45
Year of publication
1995
Pages
8171 - 8174
Database
ISI
SICI code
0040-4039(1995)36:45<8171:APMFCD>2.0.ZU;2-Q
Abstract
Significant increases in both rate and yield of metalation of p-methyl anisole (p-MA) are afforded by use of incremental and stoichiometric a mounts of TMEDA. Little metalation of the methyl protons in p-MA is ob served under all conditions.