Lm. Napolitano et al., ASYMPTOMATIC DEEP VENOUS THROMBOSIS IN THE TRAUMA PATIENT - IS AN AGGRESSIVE SCREENING PROTOCOL JUSTIFIED, The journal of trauma, injury, infection, and critical care, 39(4), 1995, pp. 651-659
The incidence and sequelae of deep venous thrombosis (DVT) in trauma p
atients are unclear because the majority of patients who develop DVT a
re asymptomatic. This study evaluated the incidence, risk factors, and
efficacy of prophylaxis for DVT in trauma patients over a 5-year peri
od. Trauma patients at high risk for DVT were evaluated biweekly with
lower extremity venous duplex scans. The DVT prophylaxis was institute
d on admission with low-dose heparin therapy and pneumatic compression
. The incidence of asymptomatic DVT identified by duplex screening was
10% (45 of 458); one pulmonary embolus occurred. Five variables were
significant from bivariate and multiple logistic regression analysis:
age (p = 0.005). Injury Severity Score (p = 0.005), length of stay (p
= 0.004). Trauma and Injury Severity Score (p = 0.01), and spinal inju
ry (p = 0.014). This analysis documents that trauma patients with thes
e risk factors are at increased risk for the development of asymptomat
ic DVT, despite prophylaxis, and warrant surveillance with venous dupl
ex sonography.