MOLECULAR-INTERACTIONS BETWEEN RETROVIRUSES AND HERPESVIRUSES

Human and animal herpesviruses are able to stimulate gene expression o f various human and animal retroviruses and the activation appears to be a common theme. It is of interest why the retroviruses can be commo nly activated by herpesviruses despite clear diversities in each mecha nism for retrovirus gene expression. In this review, three typical exa mples of the interactions; human immunodeficiency virus and human herp esviruses, avian retroviruses and Marek's disease virus, and feline im munodeficiency virus and feline herpesvirus type 1 will be given to re spond the above question on the basis of the comparative study of mole cular interactions.