Clinical blood chemistry was studied on 13 Andalusian horses with lami
nitis. Ten healthy horses were used as controls. Blood samples were ta
ken within the first 24 hr after the onset of the disease in Obel grad
e 3 before any type of treatment was given. No significant differences
were observed in the number of red blood cells and white blood cells
between Andalusian horses affected by laminitis and healthy animals. S
ignificant decrease in the number of neutrophils and increased number
of lymphocytes were noted. A significant increase in the enzymatic act
ivity of CPK, LDH and AST in these animals strongly suggested the pres
ence of muscular and hepatic disorders. The K ion increased, meeting w
ith a slight acidosis. There was also an increase of glucose and total
proteins. This fact may be a result of an excessive intake of carbohy
drates (which could cause hyperglycaemia) and a diminution of the plas
ma volume, as a consequence of fluid movement as well as the sweating
process (which could cause protein haemoconcentration).