PREVENTIVE EFFECTS OF RECOMBINANT-HUMAN-ERYTHROPOIETIN ADMINISTRATIONON ANEMIA ASSOCIATED WITH REPEATED HEMODIALYSIS IN NEPHRECTOMIZED DOGS

Authors
OISHI A HAMADA S SAKAMOTO H SHIMIZU R
Citation
A. Oishi et al., PREVENTIVE EFFECTS OF RECOMBINANT-HUMAN-ERYTHROPOIETIN ADMINISTRATIONON ANEMIA ASSOCIATED WITH REPEATED HEMODIALYSIS IN NEPHRECTOMIZED DOGS, Journal of veterinary medical science, 57(5), 1995, pp. 989-990
Citations number
12
Categorie Soggetti
Veterinary Sciences
Journal title
Journal of veterinary medical science → ACNP
ISSN journal
09167250
Volume
57
Issue
5
Year of publication
1995
Pages
989 - 990
Database
ISI
SICI code
0916-7250(1995)57:5<989:PEORA>2.0.ZU;2-U
Abstract
The preventive effects of recombinant human erythropoietin (rhEPO) adm inistration on progression of anemia were evaluated during hemodialysi s in nephrectomized dogs. In control dogs given no rhEPO, anemia gradu ally progressed with repeated hemodialysis and with little erythropoie tic response observed in the bone marrow. In dogs administered with rh EPO, however, an active erythropoietic response was induced in the bon e marrow, indicating that anemia due to hemodialysis was being prevent ed.