SUCCESSFUL TREATMENT OF PURE RED-CELL APLASIA IN SYSTEMIC LUPUS-ERYTHEMATOSUS WITH ERYTHROPOIETIN

We describe a 32-year-old woman who developed severe anemia due to pur e red cell aplasia in the course of systemic lupus erythematosus (SLE) . After failure of therapy with high doses of glucocorticoids and immu noglobulins, and despite high levels of endogenous erythropoietin, she was treated with human recombinant erythropoietin with dramatic and s ustained improvement. Based on this case and on the literature review of erythropoietin therapy in pure red cell aplasia, we suggest that er ythropoietin should be used in SLE associated pure red cell aplasia be fore cytotoxic therapy.