METAL-COMPLEXES CONTAINING BIOLOGICALLY I MPORTANT LIGANDS .80. (ETA(3)-ETA(3)-C10H16)-RU(IV) COMPLEXES WITH ALPHA-AMINO CARBOXYLATES, ALPHA-AMINO-ACID ESTERS, AND PEPTIDE ESTERS AS LIGANDS

Reactions of the chloro-bridged bis(allyl) complex [(eta(3):eta(3)-C10 H16)Ru(Cl)](2) with alpha-amino carboxylates and alpha-amino acid este rs afford the complexes (eta(3):eta(3)-C10H16)(Cl)RuNH(2)CHRCO(2) (2) and (eta(3):eta(3)-C10H16)(Cl)(2)RuNH(2)CHRCO(2)R' (3). Abstraction of chloride from 3 by Ag+ gives the N,O-chelates (eta(3):eta(3)-C10H16)( Cl)RuNH(2)CHRCO(2)-R']+BF4- (4). Cysteine methyl eater forms the N,S-c helate complex (eta(3):eta(3)-C10H16)(Cl)RuNH2CH(CO2CH3)CH2S (5), and with histidine methyl ester a dinuclear complex 6 with N,N-histidine b ridge is obtained. Compound 3d with L-Phe-OEt as ligand was characteri zed by X-ray diffraction.