Eight mouse gene loci (Atp1b2, Epo, Kit, Krt2, Mor1, Ren1, Pdgfb, and
Wnt1) that contain unidentified microsatellites were selected to detec
t simple sequence-length polymorphisms on genomic DNAs from two labora
tory strains (C57BL/6J and RF/J) and strains recently derived from the
Mus musculus species complex (CAST/Ei, MOLF/Ei, CZECH II, and M. m. d
omesticus) and from M. spretus (SPRET/Ei). All microsatellite DNA sequ
ences varied in size among some of the seven mouse strains tested. The
se new polymorphisms might be useful in the search for tumor suppresso
r genes involved in specific cancers.