Sb. Mahato et al., SYNTHESIS OF 2-METHYLINDOLE ANALOGS AND SKATOLE DIMERS UNDER FRIEDEL-CRAFTS REACTION CONDITIONS, Tetrahedron, 51(46), 1995, pp. 12667-12676
A one pot synthesis of 2-methylindole analogues and skatole dimers of
biological interest using excess amounts of the substrates and the cat
alyst and higher temperature under Friedel-Crafts acylation conditions
is reported, The products were defined by spectroscopic and single cr
ystal X-ray analysis, Rationalization for the formation of the product
s has also been attempted.