CARBONYLATIVE COUPLING OF AN AMINO ACID-DERIVED ORGANOZINC REAGENT WITH FUNCTIONALIZED ARYL IODIDES - SYNTHESIS OF KYNURENINE

Authors
JACKSON RFW TURNER D BLOCK MH
Citation
Rfw. Jackson et al., CARBONYLATIVE COUPLING OF AN AMINO ACID-DERIVED ORGANOZINC REAGENT WITH FUNCTIONALIZED ARYL IODIDES - SYNTHESIS OF KYNURENINE, Journal of the Chemical Society, Chemical Communications, (21), 1995, pp. 2207-2208
Citations number
8
Categorie Soggetti
Chemistry
Journal title
Journal of the Chemical Society, Chemical Communications → ACNP
ISSN journal
00224936
Issue
21
Year of publication
1995
Pages
2207 - 2208
Database
ISI
SICI code
0022-4936(1995):21<2207:CCOAAA>2.0.ZU;2-R
Abstract
The utility of the palladium(0) catalysed reaction of the serine-deriv ed organozinc reagent 6 with functionalized aryl iodides, under a carb on monoxide atmosphere, to give protected 4-aryl-4-oxo alpha-amino aci ds 8 is illustrated by a short synthesis of L-kynurenine.