QUANTITATIVE ELECTROENCEPHALOGRAPHIC ANALYSES IN COCAINE-PREFERRING POLYSUBSTANCE ABUSERS DURING ABSTINENCE

Quantitative electroencephalographic (QEEG) analyses are presented for a group of 90 subjects recovering from polysubstance abuse (median = 90 days abstinent) who preferentially used cocaine. QEEGs showed signi ficant decreases from normal in both absolute and relative delta power and decreased theta power in both absolute and relative power. Signif icantly increased relative but not absolute alpha and beta power was f ound. Asymmetry of frontal delta, theta, and alpha power differed from normal with right power greater than left. Globally, reduced interhem ispheric coherence was found in delta and theta bands and frontally in the beta band. An atypical EEG pattern was observed in about half of the subjects. This was a paroxysmal-like EEG alpha pattern reminiscent of vertex waves typically associated with drowsiness but lacking the waxing and waning of alpha and the slow lateral eye drift associated w ith drowsiness.