Abnormalities of thyroid function may cause irregularity or absence of
the menstrual period, inhibit pubertal development and linear growth,
and suppress reproductive function. Furthermore, pregnancy may itself
affect thyroid function. New information is presented about the diagn
osis and treatment of various forms of congenital and acquired thyroid
disease. Issues ranging from the molecular biology of thyroid hormone
resistance to public health measures developed to eliminate endemic g
oiter are addressed.