P. Clarenbach et al., RECOMMENDATIONS FOR THE DIAGNOSTIC AND TH ERAPEUTIC HANDLING OF INSOMNIA - GERMAN SLEEP SOCIETY, Nervenarzt, 66(10), 1995, pp. 723-729
There exist a variety of American and European recommendations regardi
ng treatment with hypnotics, especially the duration of treatment. The
German Sleep Society now publishes its own view to help physicians to
cope with these different recommendations, some of which are contradi
ctory. Therapy with hypnotics must include substantial information on
the type of drug, dose, timing and duration as well as information abo
ut the possibility of interval treatment. Agonists at the benzodiazepi
ne receptor, like the conventional benzodiazepines and zopiclone or zo
lpideme, are indicated in short-lasting adjustment insomnia as well as
in longlasting psychophysiological insomnia. Regarding the duration o
f prescription the German Sleep Society recommends a period of 14 days
in de novo patients, which can be repeated once only. In persisting i
nsomnias further approaches should disregard benzodiazepine receptor a
gonists, but rely on other classes of substances such as tricyclic ant
idepressants instead. If such approaches are ineffective, the intake o
f benzodiazepine receptor agonists may be extended to 6 months, when a
sleep log and objective observations have documented a true sleep def
icit, when daytime impairment arises, when rebound insomnia, organic o
r mental insomnias and dependencies have been excluded, and when the i
ndication is monitored at 14-day intervals. If the insomnia persists,
during and in spite of therapy a specialist in sleep medicine should b
e consulted. If therapy is still ineffective after 3 months of daily t
reatment, a sleep laboratory should be consulted.