J. Vaage et al., PREVENTION OF METASTASIS FROM MOUSE MAMMARY CARCINOMAS WITH LIPOSOMESCARRYING DOXORUBICIN, British Journal of Cancer, 72(5), 1995, pp. 1074-1075
Weekly treatments with doxorubicin encapsulated in long circulating, s
terically stabilised liposomes (DOX-SL) reduced the incidence of metas
tases from primary mammary carcinomas from 24 of 47 untreated mice to
3 of 23 treated mice. Toxic side-effects were limited to minor, transi
ent weight losses.