IN-VITRO ACTIVITIES OF CIPROFLOXACIN, CEFOTAXIME, CEFTRIAXONE, CHLORAMPHENICOL, AND RIFAMPIN AGAINST FULLY SUSCEPTIBLE AND MODERATELY PENICILLIN-RESISTANT NEISSERIA-MENINGITIDIS
Jm. Blondeau et Y. Yaschuk, IN-VITRO ACTIVITIES OF CIPROFLOXACIN, CEFOTAXIME, CEFTRIAXONE, CHLORAMPHENICOL, AND RIFAMPIN AGAINST FULLY SUSCEPTIBLE AND MODERATELY PENICILLIN-RESISTANT NEISSERIA-MENINGITIDIS, Antimicrobial agents and chemotherapy, 39(11), 1995, pp. 2577-2579
Moderately penicillin-resistant Neisseria meningitidis was responsible
for an outbreak of meningococcal disease in Saskatoon, Saskatchewan,
Canada in 1993. We tested fully susceptible and moderately resistant s
trains of N. meningitidis against ciprofloxacin, cefotaxime, ceftriaxo
ne, chloramphenicol, penicillin, and rifampin. Eighteen percent of the
isolates were moderately resistant to penicillin (MIC, greater than o
r equal to 0.06 mu g/ml) whereas susceptibility was 100% for the other
agents tested.