F. Mora et Jp. Ouhayoun, CLINICAL-EVALUATION OF NATURAL CORAL AND POROUS HYDROXYAPATITE IMPLANTS IN PERIODONTAL BONE-LESIONS - RESULTS OF A 1-YEAR FOLLOW-UP, Journal of clinical periodontology, 22(11), 1995, pp. 877-884
This study examines the suitability of 2 bone graft substitutes, natur
al coral skeleton (NCS) and porous hydroxyapatite (PHA) for treating p
eriodontal bone defects in human subjects, and compares them to debrid
ement alone (DEBR). A total of 30 sites in 10 patients were treated. M
easurements were made before treatment and during surgical reexaminati
on 12 months after treatment on lesions filled with NCS (10 sites), PH
A (10 sites), or DEBR (10 sites). There was no significant difference
in the use of NCS or PHA for 1, 2 wall, or combined defects for the gr
oup of parameters measured in this study (clinical probing depth, clin
ical attachment, gingival recession, bone fill, % bone fill, and crest
remodelling). Statistical analysis (Wilcoxon non-parametric test for
paired values and ANOVA for repeated measurements) revealed the benefi
cial effects of using each the biomaterials (57.4% for NCS, 58.1% for
PHA, p<0.86) as opposed to simple debridement (22.2%; p<0.002; p<0.004
).