PREPARATION OF ACRYLAMIDE MALEIC-ACID HYDROGELS AND THEIR BIOCOMPATIBILITY WITH SOME BIOCHEMICAL PARAMETERS OF HUMAN SERUM

In this study, the biocompatibility of acrylamide and acrylamide/malei c acid hydrogels prepared by using gamma-rays has been investigated ag ainst some biochemical parameters of human serum. First, the swelling kinetics of acrylamide and acrylamide/maleic acid hydrogels were inves tigated in distilled water and physiological saline solution and some swelling and diffusion parameters have been were incubated in 10 diffe rent human sera for 24 hours and their biocompatibility with some bioc hemical parameters have been investigated. No significant difference i n values before and after the test procedures have been found. It is t herefore concluded that acrylamide and acrylamide/maleic acid hydrogel s are biocompatible.