ACTION OF TETRABUTYLAMMONIUM TRIBROMIDE WITH PARASUBSTITUTED CHALCONES IN PROTIC AND APROTIC MEDIA

Authors
BERTHELOT J BENAMMAR Y DESMAZIERES B
Citation
J. Berthelot et al., ACTION OF TETRABUTYLAMMONIUM TRIBROMIDE WITH PARASUBSTITUTED CHALCONES IN PROTIC AND APROTIC MEDIA, Canadian journal of chemistry, 73(9), 1995, pp. 1526-1530
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Canadian journal of chemistry → ACNP
ISSN journal
00084042
Volume
73
Issue
9
Year of publication
1995
Pages
1526 - 1530
Database
ISI
SICI code
0008-4042(1995)73:9<1526:AOTTWP>2.0.ZU;2-#
Abstract
Bromination of the double bond of para-substituted chalcones under mil d conditions in aprotic solvents is accomplished with high yields usin g tetrabutylammonium tribromide (TBABr(3)). In methanol, the main reac tion is (alpha-beta) bromomethoxylation. Stereoselectivity, regioselec tivity, and chemioselectivity of this bromomethoxylation reaction are described.