ACTEOSIDE - A NEW ANTIHYPERTENSIVE DRUG

Acteoside is a phenylpropanoid, reported as a chemical constituent fro m different plant species, and was isolated as a pure compound on RP-H PLC from the violet flowers of Syringa vulgaris. On pharmacological ev aluation this compound exhibited a dose-dependent decrease in sytolic, diastolic and mean arterial blood pressure in normotensive pentothal anaesthetized rats. The median effective dose was 10 mg/kg and lasted for 2-3 min, whilst heart rate also decreased.