Me. Gomez et al., ACTIVITY OF OSYRIS-QUADRIPARTITA SALZM METHANOL EXTRACT ON CAPILLARY-PERMEABILITY IN RATS, PTR. Phytotherapy research, 9(7), 1995, pp. 528-530
A methanol extract of Osyris quadripartita Salzm., with high content o
f flavonoids was found to be effective in reducing the increased capil
lary permeability induced in rats by various chemical mediators involv
ed in the inflammatory process, namely histamine (HA), 5-hydroxy-tript
amine (5-HT) and bradykinin (BK), Pretreatment with the MeOH extract (
250 mg/kg i,p,) afforded significant protection against the increase i
n capillary permeability induced by HA (% protection=96.6), 5-HT (% pr
otection=53.8) and BK (% protection = 87.9).