Background. The main route of transmission of the human immunodeficien
cy virus type 1 (HIV-1) is sexual contact. A high proportion of young
adults is exposed to this mode of transmission. Therefore it is import
ant to assess the level of HIV-1 prevalence among 18 year olds in Ital
y. Methods. Available blood samples taken at the physical examination
of the military draft visit in Tuscany, Italy, have been tested in an
anonymous unlinked fashion for HIV-1 infection in 1990 and 1991. Resul
ts. In the 2 years, 4478 and 4959 men were tested, respectively, repre
senting 91.7% of all subjects included in the draft lists. Prevalence
of HIV-1 infection was 1.12 per 1000 (95% CI :0.36-2.61 per 1000) in 1
990 and 0.20 per 1000 (95% CI : 0.01-1.12) in 1991, Conclusions. Preva
lence of HIV-1 infection in the 18 year old male population in Tuscany
is close to or below 1/1000. Evidence of the presence of HIV-1 infect
ion in this population should prompt the implementation of adequate pr
evention programmes among adolescents.