DEVELOPMENT OF DISPOSABLE ELECTROCHEMICAL SENSOR WITH REPLACEABLE GLUCOSE-OXIDASE TIP

A new type of disposable electrochemical sensor, which consists of a p iece of Nafion membrane and a microdisk electrode, is developed, The N afion membrane, which is butted by the electrode to actualize the elec trochemical reaction, acts as the immobilization bed for mediator (ant hraquinone) and enzyme (glucose oxidase), The sensor is not vulnerable to being broken or contaminated, By replacing the immobilization beds with different mediators and different enzymes in series, the sensor may be employed for the rapid analysis of a multi-component sample, Th e sensor exhibits a rapid, stable response to glucose, A consecutive c alibration test shows that the original tip has an active period great er than 24 hours and the storage life time longer than 3 weeks, The li near range and the sensitivity of the original sensor are 6 mM and 0.5 2 nA/mM, respectively.