PURPOSE: We studied a case of severe bilateral Vogt-Koyanagi-Harada sy
ndrome in a 4-year-old boy METHODS: We evaluated the patient's clinica
l course. RESULTS: The patient had severe bilateral, nongranulomatous
uveitis and mild uveitic glaucoma, Initial examination and laboratory
evaluation failed to provide a diagnosis. The patient subsequently dev
eloped areas of vitiligo, alopecia, and poliosis, suggesting the diagn
osis of Vogt-Koyanagi-Harada syndrome. This diagnosis was confirmed by
the eventual development of bilateral neurosensory retinal detachment
s. Vision was lost despite aggressive therapy with corticosteroids and
chlorambucil. CONCLUSION: Although uncommon, Vogt-Koy-anagi-Harada ma
y affect young children, and may be severe.