The differences between the distal motor latencies of the 2nd lumbrica
l muscle (following stimulation of the median nerve) and the 2nd inter
osseus muscle (stimulation of the ulnar nerve) were determined in 56 h
ealthy volunteers and three patient groups: 20 with polyneuropathy (PN
P), 76 with carpal tunnel syndrome (CTS), and 16 with CTS. and coexist
ent PNP. The median-ulnar motor latency difference is less than 1,0 ms
in normals and PNP patients but is significantly prolonged in both gr
oups of CTS patients. The method has a sensitivity of 80 % in detectin
g carpal tunnel syndrome compared to 83 % of the median sensory nerve
conduction velocity and 71 % of the latency to the abductor pollicis b
revis muscle, but it turned out to be the most spesific test for patho
logical changes and is furthermore the only technique to detect a CTS
in patients with underlying polyneuropathy.