Ap. Ivanov et al., ENZYME-IMMUNOASSAY WITH BIOTIN-LABELED MO NOCLONAL-ANTIBODIES FOR TYPING OF HANTAVIRUS ANTIGENS, Voprosy virusologii, 41(6), 1996, pp. 263-265
Enzyme immunoassay with biotin-labeled monoclonal antibodies to Puumal
a virus was used for typing hantavirus antigens. The system is type-sp
ecific, that is, it detects Puumala virus only, which was demonstrated
by typing 9 hantavirus antigens in infected Vero E5 cells and by epiz
ootological analysis of an HFRS outbreak in the Yegoryevsk district of
the Moscow region in November-December 1995. The suggested system may
be used as an element of EIA screening of natural samples in analysis
of the screening results.