ENZYME-IMMUNOASSAY WITH BIOTIN-LABELED MO NOCLONAL-ANTIBODIES FOR TYPING OF HANTAVIRUS ANTIGENS

Citation
Ap. Ivanov et al., ENZYME-IMMUNOASSAY WITH BIOTIN-LABELED MO NOCLONAL-ANTIBODIES FOR TYPING OF HANTAVIRUS ANTIGENS, Voprosy virusologii, 41(6), 1996, pp. 263-265
Citations number
9
Categorie Soggetti
Virology
Journal title
ISSN journal
05074088
Volume
41
Issue
6
Year of publication
1996
Pages
263 - 265
Database
ISI
SICI code
0507-4088(1996)41:6<263:EWBMNF>2.0.ZU;2-3
Abstract
Enzyme immunoassay with biotin-labeled monoclonal antibodies to Puumal a virus was used for typing hantavirus antigens. The system is type-sp ecific, that is, it detects Puumala virus only, which was demonstrated by typing 9 hantavirus antigens in infected Vero E5 cells and by epiz ootological analysis of an HFRS outbreak in the Yegoryevsk district of the Moscow region in November-December 1995. The suggested system may be used as an element of EIA screening of natural samples in analysis of the screening results.