Lc. Borris et Mr. Lassen, THROMBOPROPHYLAXIS WITH LOW-MOLECULAR-WEIGHT HEPARIN AFTER MAJOR ORTHOPEDIC-SURGERY IS COST-EFFECTIVE, Drugs, 52, 1996, pp. 42-46
The objective of this analysis was to evaluate the socioeconomic conse
quences of routine administration of low molecular weight heparin (LMW
H) as thromboprophylaxis in patients undergoing total hip arthroplasty
, on the basis of data from a number of clinical studies. Despite the
higher direct costs associated with LMWH, this regimen was more cost e
ffective per thromboembolic complication prevented than no prophylaxis
, dextran 70, or low dose unfractionated heparin. A sensitivity analys
is was performed to address the outcome when the main factors in the e
conomic analysis were changed; this had no significant effect on the c
onclusions of the study.